BindingDB logo
myBDB logout

BDBM158071 US9023882, 370

SMILES: OC(=O)c1ccnc(c1)-n1cc(C#N)c(c1)C1=CCCCC1

InChI Key: InChIKey=GJYJEPUNDYBSKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158071   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xanthine dehydrogenase


(Bos taurus (Bovine))
BDBM158071
PNG
(US9023882, 370)
Show SMILES OC(=O)c1ccnc(c1)-n1cc(C#N)c(c1)C1=CCCCC1
Show InChI InChI=1S/C17H15N3O2/c18-9-14-10-20(11-15(14)12-4-2-1-3-5-12)16-8-13(17(21)22)6-7-19-16/h4,6-8,10-11H,1-3,5H2,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19.9n/an/an/an/an/a25



Kissei Pharmaceutical Co., Ltd

US Patent


Assay Description
Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...


US Patent US9023882 (2015)


BindingDB Entry DOI: 10.7270/Q2JW8CM6
More data for this
Ligand-Target Pair