BDBM158168 US9029360, 11

SMILES Brc1cnc2cc(nn2c1)C(=O)N1CCc2[nH]c(=O)sc2CC1

InChI Key InChIKey=NFUGEPSHTBCNFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158168   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158168(US9029360, 11)
Affinity DataIC50:  66nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent