BDBM158230 US9029370, 24

SMILES COc1cc(cc(Cl)n1)C(=O)Nc1ccc(cc1F)[C@@H]1CNCCO1

InChI Key InChIKey=WCVQGPBNASZYPQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158230   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM158230(US9029370, 24)
Affinity DataKi:  3.20nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM158230(US9029370, 24)
Affinity DataKi:  7nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
US Patent