BDBM158319 US9029370, 113
SMILES Cc1cc(cc(n1)C#N)C(=O)Nc1ccc(cc1F)[C@H]1CNCCO1
InChI Key InChIKey=DVGXXSVCMOQXEN-QGZVFWFLSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 158319
Affinity DataKi: 48.1nM ΔG°: -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...More data for this Ligand-Target Pair
Affinity DataKi: 65.4nM ΔG°: -10.2kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...More data for this Ligand-Target Pair