BDBM158352 US10118915, Compound 467::US9682966, 467::US9682966, 489

SMILES Cc1nc(no1)-c1cc2cc(F)ccc2nc1N1CCC(CC1)NC1CCCCC1

InChI Key InChIKey=WUFIJBYXWJFILI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 158352   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM158352(US9682966, 489 | US9682966, 467 | US10118915, Comp...)
Affinity DataIC50: 431nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM158352(US9682966, 489 | US9682966, 467 | US10118915, Comp...)
Affinity DataIC50: 431nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM158352(US9682966, 489 | US9682966, 467 | US10118915, Comp...)
Affinity DataIC50: 616nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent