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BDBM158510 US9034574, XX

SMILES: OC1(CC(=NN1C(=S)c1ccccc1)c1ccccc1)C(F)(F)F

InChI Key: InChIKey=RIANETHNVIQQBE-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methyl-CpG binding domain protein 2


(Homo sapiens (Human))
BDBM158510
PNG
(US9034574, XX)
Show SMILES OC1(CC(=NN1C(=S)c1ccccc1)c1ccccc1)C(F)(F)F
Show InChI InChI=1/C17H13F3N2OS/c18-17(19,20)16(23)11-14(12-7-3-1-4-8-12)21-22(16)15(24)13-9-5-2-6-10-13/h1-10,23H,11H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 470n/an/an/an/an/an/a



The Johns Hopkins University

US Patent


Assay Description
DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...


US Patent US9034574 (2015)


BindingDB Entry DOI: 10.7270/Q2RF5SSN
More data for this
Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 3


(Homo sapiens (Human))
BDBM158510
PNG
(US9034574, XX)
Show SMILES OC1(CC(=NN1C(=S)c1ccccc1)c1ccccc1)C(F)(F)F
Show InChI InChI=1/C17H13F3N2OS/c18-17(19,20)16(23)11-14(12-7-3-1-4-8-12)21-22(16)15(24)13-9-5-2-6-10-13/h1-10,23H,11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a>2.00E+5n/an/an/an/an/an/a



The Johns Hopkins University

US Patent


Assay Description
DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...


US Patent US9034574 (2015)


BindingDB Entry DOI: 10.7270/Q2RF5SSN
More data for this
Ligand-Target Pair