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BDBM158536 US9034866, 11

SMILES: CC(C)(O)C#Cc1ccc2OCC(N3CCOCC3)c3sc(nc3-c2c1)C(N)=O

InChI Key: InChIKey=NQFZEARUPTVCJV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NF-kappa-beta-inducing kinase (NF-kB)


(Homo sapiens (Human))
BDBM158536
PNG
(US9034866, 11)
Show SMILES CC(C)(O)C#Cc1ccc2OCC(N3CCOCC3)c3sc(nc3-c2c1)C(N)=O
Show InChI InChI=1S/C21H23N3O4S/c1-21(2,26)6-5-13-3-4-16-14(11-13)17-18(29-20(23-17)19(22)25)15(12-28-16)24-7-9-27-10-8-24/h3-4,11,15,26H,7-10,12H2,1-2H3,(H2,22,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
416n/an/an/an/an/an/a7.2n/a



Genentech, Inc.

US Patent


Assay Description
The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...


US Patent US9034866 (2015)


BindingDB Entry DOI: 10.7270/Q2GX49B0
More data for this
Ligand-Target Pair