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BDBM158572 US9034866, 47

SMILES: NC(=O)c1cn2CCOc3cc(F)c(cc3-c2n1)C#CC1(O)CCOC1

InChI Key: InChIKey=BBGPIHBKDNQVFP-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158572   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NF-kappa-beta-inducing kinase (NF-kB)


(Homo sapiens (Human))
BDBM158572
PNG
(US9034866, 47)
Show SMILES NC(=O)c1cn2CCOc3cc(F)c(cc3-c2n1)C#CC1(O)CCOC1
Show InChI InChI=1/C18H16FN3O4/c19-13-8-15-12(7-11(13)1-2-18(24)3-5-25-10-18)17-21-14(16(20)23)9-22(17)4-6-26-15/h7-9,24H,3-6,10H2,(H2,20,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
212n/an/an/an/an/an/a7.2n/a



Genentech Inc

US Patent


Assay Description
The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...


US Patent US9034866 (2015)


BindingDB Entry DOI: 10.7270/Q2GX49B0
More data for this
Ligand-Target Pair