BDBM158860 US9034866, 335

SMILES COC[C@@](C)(O)C#Cc1cc2-c3nc(C(N)=O)c([C@@H](O)c4ccnn4C)n3C3CC(C3)c2cc1F

InChI Key InChIKey=CEDFAOFDDPOULD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 158860   

LigandPNGBDBM158860(US9034866, 335)
Affinity DataKi:  4.10nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent

LigandPNGBDBM158860(US9034866, 335)
Affinity DataKi:  15nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent

LigandPNGBDBM158860(US9034866, 335)
Affinity DataKi: >1.20E+3nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent

LigandPNGBDBM158860(US9034866, 335)
Affinity DataKi:  1.20E+3nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent