BDBM158879 US9034866, 354

SMILES CC(C)(C)OC(=O)N1CC(C1)[C@H](O)c1c(nc2-c3cc(C#CC(C)(C)O)c(F)cc3C3CC(C3)n12)C(N)=O

InChI Key InChIKey=MREMRNHNDUQNET-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158879   

LigandPNGBDBM158879(US9034866, 354)
Affinity DataKi:  7.70nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent

LigandPNGBDBM158879(US9034866, 354)
Affinity DataKi:  35nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent