BDBM159064 US9034866, 539

SMILES CN1CC[C@@](O)(C#Cc2ccc3OC[C@@H](F)c4c(c(nn4-c3c2)C(N)=O)C(F)(F)F)C1=O

InChI Key InChIKey=TWROYIXPNRVNTG-WYRIXSBYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159064   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM159064(US9034866, 539)
Affinity DataKi:  2.30nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM159064(US9034866, 539)
Affinity DataKi:  3.10nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent