BDBM159182 US9034866, 659
SMILES Cc1cnc(o1)[C@@](C)(O)C#Cc1ccc2C3CC(C3)n3cc(nc3-c2c1)C(N)=O
InChI Key InChIKey=RODIOQSCTKCZKO-MRHLONDUSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 159182
Affinity DataKi: 0.290nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of full length GST-tagged human PRKD1 expressed in Baculovirus expression system using ATP as substrate incubated for 1 to 2 hrs by transc...More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+3nMAssay Description:Inhibition of NIK (unknown origin) using ATP as substrate by transcreener ADP assay based fluorescence correlation spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair