BDBM159300 US10093663, Example 10::US9682968, Example-10

SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC(C)(CC1c1ccc(cc1)C(N)=O)OC

InChI Key InChIKey=PTVJLZRVTIPNBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159300   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159300(US9682968, Example-10 | US10093663, Example 10)
Affinity DataIC50: 11nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159300(US9682968, Example-10 | US10093663, Example 10)
Affinity DataIC50: 1.10E+4nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent