BindingDB logo
myBDB logout

BDBM159371 US9034907, 24

SMILES: Cc1cn(CCCn2c(=S)[nH]c3sc4CCCCCCc4c3c2=O)cn1

InChI Key: InChIKey=BGDPLDYXJZZLFQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159371   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM159371
PNG
(US9034907, 24)
Show SMILES Cc1cn(CCCn2c(=S)[nH]c3sc4CCCCCCc4c3c2=O)cn1
Show InChI InChI=1S/C19H24N4OS2/c1-13-11-22(12-20-13)9-6-10-23-18(24)16-14-7-4-2-3-5-8-15(14)26-17(16)21-19(23)25/h11-12H,2-10H2,1H3,(H,21,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
632 -8.59 2.69E+3n/an/an/an/a8.030



Probiodrug AG

US Patent


Assay Description
Fluorometric Assays: All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was eval...


US Patent US9034907 (2015)


BindingDB Entry DOI: 10.7270/Q2V69HBJ
More data for this
Ligand-Target Pair