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BDBM159380 US9034907, 35

SMILES: O=c1n(CCCn2ccnc2)c(=S)[nH]c2sc3CCCc3c12

InChI Key: InChIKey=MSBHQHBFHGRWJF-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM159380
PNG
(US9034907, 35)
Show SMILES O=c1n(CCCn2ccnc2)c(=S)[nH]c2sc3CCCc3c12
Show InChI InChI=1S/C15H16N4OS2/c20-14-12-10-3-1-4-11(10)22-13(12)17-15(21)19(14)7-2-6-18-8-5-16-9-18/h5,8-9H,1-4,6-7H2,(H,17,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
615 -8.61 5.85E+3n/an/an/an/a8.030



Probiodrug AG

US Patent


Assay Description
Fluorometric Assays: All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was eval...


US Patent US9034907 (2015)


BindingDB Entry DOI: 10.7270/Q2V69HBJ
More data for this
Ligand-Target Pair