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BDBM159675 US9035059, 8-14

SMILES: CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCCOC3CCCC3)cc2F)cc1

InChI Key: InChIKey=TVVBXYVBLRLBQK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159675   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159675
PNG
(US9035059, 8-14)
Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCCOC3CCCC3)cc2F)cc1
Show InChI InChI=1S/C35H45FN2O4S/c1-35(2,3)29-12-9-26(10-13-29)17-19-38-20-18-27-23-32(15-11-28(27)25-38)43(39,40)37-34-16-14-31(24-33(34)36)42-22-6-21-41-30-7-4-5-8-30/h9-16,23-24,30,37H,4-8,17-22,25H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 68n/an/an/an/an/a25



Taisho Pharmaceutical Co., Ltd

US Patent


Assay Description
An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...


US Patent US9035059 (2015)


BindingDB Entry DOI: 10.7270/Q2B856WH
More data for this
Ligand-Target Pair