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BDBM160048 US9040528, 181

SMILES: C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)S(C)=O)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=XKCVSPQEFVJYLX-ZQTFFFODNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160048   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA Gyrase


(Escherichia coli (strain K12))
BDBM160048
PNG
(US9040528, 181)
Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)S(C)=O)C(=O)NC(=O)NC1=O
Show InChI InChI=1/C19H19FN4O6S/c1-7-6-24-12-9(4-10-13(11(12)20)30-23-15(10)31(3)28)5-19(14(24)8(2)29-7)16(25)21-18(27)22-17(19)26/h4,7-8,14H,5-6H2,1-3H3,(H2,21,22,25,26,27)/t7-,8+,14-,31?/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.30E+3n/an/an/an/a7.5n/a



AstraZeneca AB

US Patent


Assay Description
In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...


US Patent US9040528 (2015)


BindingDB Entry DOI: 10.7270/Q2PG1QG0
More data for this
Ligand-Target Pair