BindingDB PrimarySearch

BDBM16018 14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-8-one::CHEMBL7064::ChemBiol10705 Compound 4::JMC517015 Compound 2::SP 600125::SP-600125::SP600125::cid_8515::dibenzo[cd,g]indazol-6(2H)-one

SMILES: O=C1c2ccccc2-c2n[nH]c3cccc1c23

InChI Key: InChIKey=ACPOUJIDANTYHO-UHFFFAOYSA-N

Data: 89 IC50 3 Kd 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 93 hits for monomerid = 16018
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase NIM1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek6 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 26 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
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SAFB-like transcription modulator (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Maternal embryonic leucine zipper kinase (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 4 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity immunoglobulin gamma Fc receptor I (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase haspin (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	8.98E+3	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic elongation factor 2 kinase (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-2 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM16018 (cid_8515 \| SP 600125 \| ChemBiol10705 Compound 4 \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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