BDBM16040 (3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-(N-methylmethanesulfonamido)phenyl)methyl (2R)-2-amino-2-methyl-3-phenylpropanoate::3-[4-benzyl-4-(hydroxymethyl)-4,5-dihydro-1,3-oxazol-2-yl]-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide::tertiary carbinamine derived inhibitor 7

SMILES: C[C@@H](NC(=O)c1cc(COC(=O)[C@](C)(N)Cc2ccccc2)cc(c1)N(C)S(C)(=O)=O)c1ccc(F)cc1

InChI Key: InChIKey=PTQRJCCBUDSHTQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM16040 ((3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-(N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	4.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16040 ((3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-(N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM16040 ((3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-(N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair