BDBM160573 US9682980, 3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

SMILES FC(F)(F)c1c(cnn2c(CC3CC3)nnc12)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=WLJJIQZGOMUFEA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160573   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160573(US9682980, 3-(Cyclopropylmethyl)-7-(4-phenylpiperi...)
Affinity DataEC50:  3nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent