BDBM160697 US9045500, 19

SMILES CO[C@H]1CC[C@@]2(Cc3ccc(cc3[C@]22N=C(N)c3ccc(cc23)C#N)C#CC2CC2)CC1

InChI Key InChIKey=JZQLUTHTSVLPQE-MWVDVNALSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160697   

TargetBeta-secretase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM160697(US9045500, 19)
Affinity DataIC50:  5.90nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In DepthDetails US Patent