BDBM160907 US10093655, Example 77::US11014909, Example 77::US9107923, 77

SMILES Cc1cnc(=O)n(C)c1-c1ccc(Oc2ncccc2C(F)(F)F)cc1C

InChI Key InChIKey=DYFZGOFCSNGJAB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 160907   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160907(US9107923, 77 | US10093655, Example 77 | US1101490...)
Affinity DataKi:  337nMAssay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160907(US9107923, 77 | US10093655, Example 77 | US1101490...)
Affinity DataKi:  337nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160907(US9107923, 77 | US10093655, Example 77 | US1101490...)
Affinity DataKi:  337nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent