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BDBM161028 US9108905, 17

SMILES: CC\C(=N/O)\C(\C)=C\c1ccc(F)c(C)c1

InChI Key: InChIKey=WRHHATMLNUQQTB-MZRBSKCNSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM161028
PNG
(US9108905, 17)
Show SMILES CC\C(=N/O)\C(\C)=C\c1ccc(F)c(C)c1
Show InChI InChI=1S/C13H16FNO/c1-4-13(15-16)10(3)8-11-5-6-12(14)9(2)7-11/h5-8,16H,4H2,1-3H3/b10-8+,15-13+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+5n/an/an/an/an/a25



AbbVie Inc

US Patent


Assay Description
Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...


US Patent US9108905 (2015)


BindingDB Entry DOI: 10.7270/Q2ZS2V7G
More data for this
Ligand-Target Pair