BDBM16108 3-carbamoyl-5-[4-(4-methylphenyl)phenyl]benzoic acid::5-carbamoyl-4 -methyl-1,1 :4 ,1 -terphenyl-3-carboxylic acid::AMX03::Brequinar-derived asymmetric terphenyl compound

SMILES Cc1ccc(cc1)-c1ccc(cc1)-c1cc(cc(c1)C(O)=O)C(N)=O

InChI Key InChIKey=DLRKWTKJHPRPPF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16108   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Cornell University

LigandPNGBDBM16108(3-carbamoyl-5-[4-(4-methylphenyl)phenyl]benzoic ac...)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.40kcal/molepH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed