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BDBM161157 US9051265, 65

SMILES: C[C@H](NC(=O)c1ccc2n(Cc3cc(O[C@@H](C)C(O)=O)ccc3Cl)c(C)c(C)c2c1)c1cccc(c1)C(C)(C)C

InChI Key: InChIKey=BOOVJQGXQIGBIS-MGRUGCKGNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM161157
PNG
(US9051265, 65)
Show SMILES C[C@H](NC(=O)c1ccc2n(Cc3cc(O[C@@H](C)C(O)=O)ccc3Cl)c(C)c(C)c2c1)c1cccc(c1)C(C)(C)C
Show InChI InChI=1/C33H37ClN2O4/c1-19-21(3)36(18-25-16-27(12-13-29(25)34)40-22(4)32(38)39)30-14-11-24(17-28(19)30)31(37)35-20(2)23-9-8-10-26(15-23)33(5,6)7/h8-17,20,22H,18H2,1-7H3,(H,35,37)(H,38,39)/t20-,22-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.60n/an/an/an/an/an/a



The Scripps Research Institute

US Patent


Assay Description
The assay was performed according to manufacturer protocol. A mixture of 5 nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan- PPAR Green, an...


US Patent US9051265 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JSW
More data for this
Ligand-Target Pair