BDBM161389 US10124003, Ref. Ex. Compound 3::US10835536, Ex. Comp 2::US10894048, Ex Comp 2::US9108973, 2

SMILES: COc1cc(cc(c1)OC)C#Cc2c3c(ncnc3n(n2)[C@H]4CCN(C4)C(=O)C=C)N

InChI Key: InChIKey=KEIPNCCJPRMIAX-UHFFFAOYSA-N

Data: 37 IC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 161389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	25
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM161389 (US9108973, 2 | US10124003, Ref. Ex. Compound 3 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair