BDBM161521 US9108983, Example 52

SMILES CCNC(=O)NCc1ccc(C(=O)N2Cc3ccccc3C[C@H]2C)c(c1)-c1cc(C(=O)N(C)c2ccc(O)cc2)c(C)n1C

InChI Key InChIKey=MBYDIBWADVOSTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161521   

TargetApoptosis regulator Bcl-2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM161521(US9108983, Example 52)
Affinity DataIC50: 28.9nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent