BDBM161527 US9108983, Example 58

SMILES C[C@@H]1Cc2ccccc2CN1C(=O)c1ccc(CCNC(=O)Nc2ccccc2)cc1-c1cc(C(=O)N(C)c2ccc(O)cc2)c(C)n1C

InChI Key InChIKey=LBZQBUVWSNPYJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161527   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161527(US9108983, Example 58)
Affinity DataIC50: 133nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent