BDBM161613 US9108983, Example 430

SMILES Cc1c(cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3CC2C(F)(F)F)n1C)C(=O)N(c1ccc(O)cc1)c1cnc2n(C)ccc2c1

InChI Key InChIKey=OYLLJXFIWJYSSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161613   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161613(US9108983, Example 430)
Affinity DataIC50: 19.9nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent