BDBM161650 US9682976, 109::US9682976, 110

SMILES Cn1nnn(-c2cc(Nc3ncc(F)c(N[C@@H]4C[C@@H]5CCCN5C(C)(C)C4)n3)c(F)cc2OC2CCOC2)c1=O

InChI Key InChIKey=WHKQTJGESNASRF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161650   

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161650(US9682976, 110 | US9682976, 109)
Affinity DataEC50: <500nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161650(US9682976, 110 | US9682976, 109)
Affinity DataEC50: <500nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent