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BDBM161809 US9682976, 250

SMILES: CC1(C)C[C@@H](C[C@@H]2CCCN12)Nc1nc(Nc2ccc3OC(C)(C)c4nn(C(CO)CCl)c(=O)n4-c3c2)ncc1F

InChI Key: InChIKey=ZWKZWDGMMPLWLU-IDHNHROENA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161809   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-2 (IL-2)


(Homo sapiens (Human))
BDBM161809
PNG
(US9682976, 250)
Show SMILES CC1(C)C[C@@H](C[C@@H]2CCCN12)Nc1nc(Nc2ccc3OC(C)(C)c4nn(C(CO)CCl)c(=O)n4-c3c2)ncc1F
Show InChI InChI=1/C28H36ClFN8O3/c1-27(2)12-17(10-18-6-5-9-36(18)27)32-23-20(30)14-31-25(34-23)33-16-7-8-22-21(11-16)37-24(28(3,4)41-22)35-38(26(37)40)19(13-29)15-39/h7-8,11,14,17-19,39H,5-6,9-10,12-13,15H2,1-4H3,(H2,31,32,33,34)/t17-,18+,19?/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+4n/an/an/an/a



Rigel Pharmaceuticals, Inc

US Patent


Assay Description
Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...


US Patent US9682976 (2017)


BindingDB Entry DOI: 10.7270/Q2DJ5CT2
More data for this
Ligand-Target Pair