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BDBM161859 US9682976, 291

SMILES: Cn1nc2COc3ccc(Nc4ncc(F)c(N[C@@H]5C[C@@H]6CCCN6C(C)(C)C5)n4)cc3-n2c1=O

InChI Key: InChIKey=HRPQTQWTNMOUIS-REIYMHPCNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161859   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-2 (IL-2)


(Homo sapiens (Human))
BDBM161859
PNG
(US9682976, 291)
Show SMILES Cn1nc2COc3ccc(Nc4ncc(F)c(N[C@@H]5C[C@@H]6CCCN6C(C)(C)C5)n4)cc3-n2c1=O
Show InChI InChI=1/C24H29FN8O2/c1-24(2)11-15(9-16-5-4-8-32(16)24)27-21-17(25)12-26-22(29-21)28-14-6-7-19-18(10-14)33-20(13-35-19)30-31(3)23(33)34/h6-7,10,12,15-16H,4-5,8-9,11,13H2,1-3H3,(H2,26,27,28,29)/t15-,16+/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<500n/an/an/an/a



Rigel Pharmaceuticals, Inc

US Patent


Assay Description
Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...


US Patent US9682976 (2017)


BindingDB Entry DOI: 10.7270/Q2DJ5CT2
More data for this
Ligand-Target Pair