BDBM16211 5-methyl-4-phenyl-1H-pyrazole::CHEMBL228114::pyrazole-based inhibitor 1

SMILES Cc1[nH]ncc1-c1ccccc1

InChI Key InChIKey=XTXZCNATVCIKTR-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16211   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM16211(5-methyl-4-phenyl-1H-pyrazole | CHEMBL228114 | pyr...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of protein kinase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16211(5-methyl-4-phenyl-1H-pyrazole | CHEMBL228114 | pyr...)
Affinity DataIC50:  8.00E+4nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed