BDBM162123 US9051279, 106

SMILES: CC(C)Oc1cc2c(cc1OC)CC(=O)N([C@H]2c3ccc(cc3)Cl)c4ccc(cc4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C

InChI Key: InChIKey=CLRSLRWKONPSRQ-UHFFFAOYSA-N

Data: 3 KI  13 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 162123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Baculoviral IAP repeat-containing protein 2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase XIAP (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a
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Protein Mdm4 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Protein Mdm4 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein Mdm4 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Dog)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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E3 ubiquitin-protein ligase Mdm2 (Mouse)	BDBM162123 (US9051279, 106) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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