BDBM16224 6-phenylpurine compound 6::N-methyl-1-[4-(9H-purin-6-yl)phenyl]methanamine::methyl({[4-(9H-purin-6-yl)phenyl]methyl})amine

SMILES CNCc1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key InChIKey=VRGSDHJXBVCQEL-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16224   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16224(6-phenylpurine compound 6 | N-methyl-1-[4-(9H-puri...)
Affinity DataIC50:  6.90E+3nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16224(6-phenylpurine compound 6 | N-methyl-1-[4-(9H-puri...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16224(6-phenylpurine compound 6 | N-methyl-1-[4-(9H-puri...)
Affinity DataIC50:  5.20E+3nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair