BDBM162321 US10307427, Compound 12::US9051313, 12

SMILES O=C(Nc1csc(n1)-c1nncn1C1CC1)c1cc(c(cn1)N1CCCCC1)-n1cnc(c1)C1CC1

InChI Key InChIKey=MPBCXZFLFOKYBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162321   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162321(US10307427, Compound 12 | US9051313, 12)
Affinity DataIC50:  2nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162321(US10307427, Compound 12 | US9051313, 12)
Affinity DataIC50:  2nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent