BDBM162327 US9669028, 74 3-methyl-5-(3-(pyrrolidin-1-yl)pyrazin-2-yl)-1H-pyrazolo[3,4-b]pyridine

SMILES Cc1n[nH]c2ncc(cc12)-c1nccnc1N1CCCC1

InChI Key InChIKey=SVDWEPGHMMNURE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162327   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162327(US9669028, 74 3-methyl-5-(3-(pyrrolidin-1-yl)pyraz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162327(US9669028, 74 3-methyl-5-(3-(pyrrolidin-1-yl)pyraz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent