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BDBM162910 US9056865, A-37

SMILES: Cc1cccnc1-c1cc(ncc1Cl)N1CCC(COCCCO)CC1

InChI Key: InChIKey=INFRSQBJECEGFU-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162910   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein- coupled-like receptor Smoothened (Smo)


(Homo sapiens (Human))
BDBM162910
PNG
(US9056865, A-37)
Show SMILES Cc1cccnc1-c1cc(ncc1Cl)N1CCC(COCCCO)CC1
Show InChI InChI=1S/C20H26ClN3O2/c1-15-4-2-7-22-20(15)17-12-19(23-13-18(17)21)24-8-5-16(6-9-24)14-26-11-3-10-25/h2,4,7,12-13,16,25H,3,5-6,8-11,14H2,1H3
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Similars

Article
US Patent
n/an/a 209n/an/an/an/an/a25



Pfizer Inc

US Patent


Assay Description
For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...


US Patent US9056865 (2015)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q2R49PH7
More data for this
Ligand-Target Pair