BDBM163114 US9062026, Table III, Compound 42

SMILES COc1nc2ccccc2n1-c1nc2CCNCc2c(NCc2ccccc2)n1

InChI Key InChIKey=HVVDVXJCOGZSOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163114   

TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163114(US9062026, Table III, Compound 42)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163114(US9062026, Table III, Compound 42)
Affinity DataIC50: <2.00E+3nMpH: 7.5 T: 2°CAssay Description:The ATPase assay is performed according the following protocol: Purified enzyme (20 nM p97), substrate (20 uM ATP) and a dose titration of compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent