BDBM163243 US9062045, Comparator No. 1 (JNJ-38877605)

SMILES: Cn1cc(cn1)-c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1

InChI Key: InChIKey=JRWCBEOAFGHNNU-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 163243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor/Nucleoprotein TPR (Mouse)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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