BDBM163400 US9687479, 275 1-(5-[(5-chlorothiophen-2-yl)methyl]amino-4-fluoro-3-phenyl-1H-pyrazol-1-yl)-3-hydroxy-2,2-dimethylpropan-1-one

SMILES CC(C)(CO)C(=O)n1nc(c(F)c1NCc1ccc(Cl)s1)-c1ccccc1

InChI Key InChIKey=YMUNSTMHICDGNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163400   

TargetPlasma kallikrein(Human)
Verseon

US Patent
LigandPNGBDBM163400(US9687479, 275 1-(5-[(5-chlorothiophen-2-yl)methyl...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent