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BDBM163692 ISOCARBOXAZID::Isocarboxazid (ICD)::Isocarboxazide::Marplan

SMILES: Cc1cc(no1)C(=O)NNCc1ccccc1

InChI Key: InChIKey=XKFPYPQQHFEXRZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163692   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
8-Oxoguanine DNA glycosylase-1 (OGG1)


(Homo sapiens (Human))
BDBM163692
PNG
(ISOCARBOXAZID | Isocarboxazid (ICD) | Isocarboxazi...)
Show SMILES Cc1cc(no1)C(=O)NNCc1ccccc1
Show InChI InChI=1S/C12H13N3O2/c1-9-7-11(15-17-9)12(16)14-13-8-10-5-3-2-4-6-10/h2-7,13H,8H2,1H3,(H,14,16)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Oregon Health & Science University



Assay Description
A total of 4 ÁL of OGG1 (125 nM) was mixed with 1 ÁL of inhibitor. In a separate tube, 1 ÁL of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...


ACS Chem Biol 10: 2334-43 (2015)

More data for this
Ligand-Target Pair