BDBM164185 US9687479, 402 N-benzyl-1-[(furan-3-yl)carbonyl]-3-(pyridin-4-yl)-1H-1,2,4-triazol-5-amine::US9687479, 407 N-benzyl-3-(pyridin-4-yl)-1-[(thiophen-3-yl)carbonyl]-1H-1,2,4-triazol-5-amine

SMILES O=C(c1ccoc1)n1nc(nc1NCc1ccccc1)-c1ccncc1

InChI Key InChIKey=DDZQUXJBMPJFPD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 164185   

TargetPlasma kallikrein(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM164185(US9687479, 402 N-benzyl-1-[(furan-3-yl)carbonyl]-3...)
Affinity DataIC50:  5.50E+4nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM164185(US9687479, 402 N-benzyl-1-[(furan-3-yl)carbonyl]-3...)
Affinity DataIC50:  550nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM164185(US9687479, 402 N-benzyl-1-[(furan-3-yl)carbonyl]-3...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Recombinant human tissue kallikrein (KLK1) was obtained from R&D Systems. Pro-Phe-Arg-AMC (I-1295) substrate was obtained from Bachem. KLK1 enzyme is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent