BDBM16419 2-phenylacetic acid::Benzeneacetic acid::CHEMBL1044::Phenylacetate, XIX::Phenylacetic acid::phenylacetate

SMILES OC(=O)Cc1ccccc1

InChI Key InChIKey=WLJVXDMOQOGPHL-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 Kd  1 EC50

PDB links: 10 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 16419   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKi:  9.60E+4nM ΔG°:  -5.48kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [C299A](Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKi:  3.03E+5nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKi:  3.60E+5nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetProlyl 4-hydroxylase subunit alpha-1(Gallus gallus (Chicken))
University Of Oulu

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOlfactory receptor class A-like protein 1(Danio rerio (Zebrafish))
German Institute Of Human Nutrition Potsdam-Rehbruecke

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataEC50:  3.05E+4nMpH: 7.4Assay Description:Briefly, HEK 293T cells stably expressing the G protein-chimera Gα16gust44 were seeded onto 96-well plates coated with 10 μg/ml of poly-D-l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataKd: >5.00E+7nMAssay Description:Binding affinity against Lck SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16419(2-phenylacetic acid | Benzeneacetic acid | CHEMBL1...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair