BDBM164243 US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione (Cpd. No. 2)

SMILES: CC1(NC(=O)C2=CC=C(C(=O)N21)Nc3ccncn3)C

InChI Key: InChIKey=YUDKTFUCCPOVGR-UHFFFAOYSA-N

Data: 8 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 164243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Human)	BDBM164243 (US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair