BDBM16430 (2E)-3-phenylprop-2-enoic acid::CHEMBL27246::Cinnamic acid::Zimtsaeure::Zimtsaeure | trans-Cinnamate::t-Cinnamic acid::trans-Cinnamate

SMILES: c1ccc(cc1)\C=C\C(=O)O

InChI Key: InChIKey=WBYWAXJHAXSJNI-UHFFFAOYSA-N

Data: 5 KI  10 IC50

PDB links: 8 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 16430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+6	n/a	n/a	n/a	n/a	8.0	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Amyloid-beta precursor protein (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL62 (Baker's yeast)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2 (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	685	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 3 (Escherichia coli)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hydroxycarboxylic acid receptor 2 (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80E+5	-4.84	n/a	n/a	n/a	n/a	n/a	7.0	25
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Aldo-keto reductase family 1 member B1 [W220Y,C299A] (Human)	BDBM16430 (Zimtsaeure | CHEMBL27246 | trans-Cinnamate | (2E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.39E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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