BDBM164424 US9066954, 62

SMILES COc1cnc2c(OCc3cnc4ccc(nn34)-c3cc(F)c(F)c(F)c3)ccnc2c1

InChI Key InChIKey=XDTJDXFAINRNAT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164424   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM164424(US9066954, 62)
Affinity DataKi:  1.70nM ΔG°:  -12.0kcal/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In DepthDetails US Patent