BDBM164435 US9066954, 86

SMILES COc1ccc2c(OCc3nnc4c(F)cc(cn34)-c3cnc(C)s3)ccnc2c1

InChI Key InChIKey=IAODRBSFNMKRPP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164435   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM164435(US9066954, 86)
Affinity DataKi:  2.40nM ΔG°:  -11.8kcal/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In DepthDetails US Patent