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BDBM164455 US9066954, 187

SMILES: COc1cnc2c(NCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1

InChI Key: InChIKey=SIIJCIDVDYNPDV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164455   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164455
PNG
(US9066954, 187)
Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1
Show InChI InChI=1S/C21H18N8O2/c1-28-12-13(3-6-20(28)30)15-4-5-18-25-26-19(29(18)27-15)11-23-16-7-8-22-17-9-14(31-2)10-24-21(16)17/h3-10,12H,11H2,1-2H3,(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
4.90 -11.4n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair