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BDBM164470 US9066954, 295

SMILES: COc1cnc2c(NCc3nnc4c(F)cc(cn34)-c3cc(C)ns3)ccnc2c1

InChI Key: InChIKey=BGCVPRDNBVSVKW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164470   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164470
PNG
(US9066954, 295)
Show SMILES COc1cnc2c(NCc3nnc4c(F)cc(cn34)-c3cc(C)ns3)ccnc2c1
Show InChI InChI=1S/C20H16FN7OS/c1-11-5-17(30-27-11)12-6-14(21)20-26-25-18(28(20)10-12)9-23-15-3-4-22-16-7-13(29-2)8-24-19(15)16/h3-8,10H,9H2,1-2H3,(H,22,23)
PDB
MMDB

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Similars

US Patent
26.9 -10.4n/an/an/an/an/a8.027



Amgen Inc

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair